@import"https://fonts.googleapis.com/css2?family=Cormorant+Garamond:ital,wght@0,300;0,400;0,600;0,700;1,300;1,400&family=DM+Sans:wght@300;400;500;600&display=swap";:root{--deep-navy: #0E1F38;--midnight: #07131F;--sapphire: #1B4F8A;--cerulean: #2E7DC4;--ice: #A8CBE8;--gold: #C9A84C;--warm-white: #F7F4EF;--cream: #EDE9E1;--charcoal: #2C2C2C;--muted: #6B7A8D}*{box-sizing:border-box;margin:0;padding:0}body{font-family:DM Sans,sans-serif;background:var(--warm-white);color:var(--charcoal);line-height:1.6}.cover{background:var(--midnight);color:#fff;min-height:100vh;display:flex;flex-direction:column;justify-content:center;padding:80px;position:relative;overflow:hidden}.cover:before{content:"";position:absolute;top:-200px;right:-200px;width:700px;height:700px;border-radius:50%;background:radial-gradient(circle,rgba(44,125,196,.18) 0%,transparent 70%);pointer-events:none}.cover-label{font-size:11px;font-weight:500;letter-spacing:4px;text-transform:uppercase;color:var(--gold);margin-bottom:32px}.cover h1{font-family:Cormorant Garamond,serif;font-size:clamp(48px,7vw,88px);font-weight:300;line-height:1.05;max-width:800px;margin-bottom:32px}.cover h1 em{font-style:italic;color:var(--ice)}.cover p{font-size:16px;color:#fff9;max-width:560px;margin-bottom:48px;font-weight:300}.cover-meta{display:flex;gap:48px;flex-wrap:wrap}.cover-meta-item{border-left:2px solid var(--gold);padding-left:16px}.cover-meta-item .label{font-size:10px;letter-spacing:3px;text-transform:uppercase;color:var(--gold);margin-bottom:4px}.cover-meta-item .value{font-family:Cormorant Garamond,serif;font-size:20px;color:#fff}.section-wrap{max-width:1100px;margin:0 auto;padding:80px 40px}.section-label{font-size:10px;letter-spacing:4px;text-transform:uppercase;color:var(--gold);margin-bottom:12px;font-weight:500}.section-title{font-family:Cormorant Garamond,serif;font-size:clamp(32px,5vw,54px);font-weight:400;line-height:1.1;color:var(--deep-navy);margin-bottom:16px}.section-subtitle{font-size:16px;color:var(--muted);max-width:620px;font-weight:300;margin-bottom:48px}.sb-section-header{background:var(--deep-navy);color:#fff;padding:20px 40px;display:flex;align-items:center;gap:20px;position:sticky;top:0;z-index:10}.sb-section-num{font-family:Cormorant Garamond,serif;font-size:48px;font-weight:300;color:var(--gold);line-height:1;min-width:60px}.sb-section-info h2{font-family:Cormorant Garamond,serif;font-size:26px;font-weight:400;margin-bottom:2px}.sb-section-info .sb-purpose{font-size:12px;color:var(--ice);letter-spacing:1px;font-weight:300}.wireframe-container{background:var(--cream);padding:48px 40px;border-bottom:1px solid #ddd}.wireframe{background:#fff;border:1px solid #d0ccc4;border-radius:4px;padding:40px;max-width:960px;margin:0 auto;box-shadow:0 4px 24px #0000000f;font-size:14px}.wireframe-nav{display:flex;justify-content:space-between;align-items:center;padding-bottom:20px;border-bottom:1px solid #e5e5e5;margin-bottom:32px}.wf-logo{font-family:Cormorant Garamond,serif;font-size:20px;color:var(--deep-navy);font-weight:600}.wf-nav-links{display:flex;gap:20px;font-size:12px;color:var(--muted)}.wf-cta-btn{background:var(--gold);color:#fff;padding:8px 20px;font-size:12px;border-radius:2px;font-weight:500;letter-spacing:1px;text-transform:uppercase}.wf-hero:after{content:"";position:absolute;top:0;right:0;width:300px;height:100%;background:radial-gradient(circle at 70% 50%,rgba(44,125,196,.25) 0%,transparent 60%)}.wf-hero-kicker{font-size:10px;letter-spacing:4px;text-transform:uppercase;color:var(--gold);margin-bottom:16px}.wf-hero h2{font-family:Cormorant Garamond,serif;font-size:44px;font-weight:300;line-height:1.1;margin-bottom:16px;max-width:620px}.wf-hero h2 em{font-style:italic;color:var(--ice)}.wf-hero p{font-size:15px;color:#ffffffbf;max-width:520px;margin-bottom:28px;font-weight:300}.wf-hero-btns{display:flex;gap:16px}.wf-btn-primary{background:var(--gold);color:#fff;padding:12px 28px;font-size:13px;letter-spacing:1px;text-transform:uppercase;font-weight:500;cursor:pointer}.wf-btn-secondary{border:1px solid rgba(255,255,255,.4);color:#fff;padding:12px 28px;font-size:13px;letter-spacing:1px;text-transform:uppercase;font-weight:300;cursor:pointer}.wf-hero-stats{display:flex;gap:40px;margin-top:48px;padding-top:32px;border-top:1px solid rgba(255,255,255,.15);flex-wrap:wrap}.wf-stat .num{font-family:Cormorant Garamond,serif;font-size:36px;font-weight:300;color:#fff}.wf-stat .num sup{font-size:18px;color:var(--gold)}.wf-stat .desc{font-size:11px;color:#ffffff80;text-transform:uppercase;letter-spacing:2px}.wf-footnote-block{margin:16px 0 0;padding:12px 16px;border-top:1px solid rgba(255,255,255,.15);font-size:11px;color:#ffffff73;font-style:italic}.wf-block{margin-bottom:32px}.wf-block h3{font-family:Cormorant Garamond,serif;font-size:26px;font-weight:400;color:var(--deep-navy);margin-bottom:8px}.wf-block p{font-size:14px;color:var(--muted);margin-bottom:8px;font-weight:300}.annotation{font-size:11px;background:#fff9ed;border-left:3px solid var(--gold);padding:8px 12px;color:#7a5c00;font-style:italic;margin-top:8px}.wf-grid-3{display:grid;grid-template-columns:repeat(3,1fr);gap:20px;margin:24px 0}.wf-grid-2{display:grid;grid-template-columns:repeat(2,1fr);gap:24px;margin:24px 0}.wf-grid-4{display:grid;grid-template-columns:repeat(4,1fr);gap:16px;margin:24px 0}.wf-card{background:var(--warm-white);border:1px solid #e0ddd6;padding:24px;border-radius:2px}.wf-card.featured{background:#edf4fb;border:1px solid var(--cerulean)}.wf-card.lead-program{background:linear-gradient(135deg,#f8f4e8,#faf7ee);border:1px solid var(--gold);position:relative}.wf-card.lead-program:before{content:"LEAD PROGRAM";position:absolute;top:-10px;left:16px;background:var(--gold);color:#fff;font-size:9px;letter-spacing:2px;padding:3px 10px;font-weight:600}.wf-card .card-icon{font-size:24px;margin-bottom:12px}.wf-card h4{font-family:Cormorant Garamond,serif;font-size:20px;color:var(--deep-navy);margin-bottom:6px;font-weight:500}.wf-card p{font-size:13px;color:var(--muted);font-weight:300}.wf-card .wf-tag{display:inline-block;background:var(--deep-navy);color:var(--ice);font-size:10px;letter-spacing:2px;text-transform:uppercase;padding:3px 8px;margin-top:12px}.wf-card .wf-tag.featured-tag{background:var(--cerulean)}.wf-card a.pub-link{display:block;font-size:11px;color:var(--cerulean);margin-top:10px;text-decoration:none}.wf-card a.pub-link:hover{text-decoration:underline;color:var(--sapphire)}a.pub-link-italic{color:var(--cerulean);text-decoration:none;font-style:italic;border-bottom:1px dotted var(--cerulean)}a.pub-link-italic:hover{color:var(--sapphire);border-bottom:1px solid var(--sapphire)}a.pub-link-inline{color:var(--cerulean);text-decoration:none;border-bottom:1px dotted var(--cerulean)}a.pub-link-inline:hover{color:var(--sapphire);border-bottom:1px solid var(--sapphire)}.wf-dark-band{background:var(--deep-navy);color:#fff;padding:40px;margin:32px -40px}.wf-dark-band h3{font-family:Cormorant Garamond,serif;font-size:28px;font-weight:300;margin-bottom:16px}.wf-dark-band p{font-size:14px;color:#ffffffb3;font-weight:300;max-width:680px}.wf-timeline{position:relative;padding-left:32px;border-left:2px solid var(--ice);margin:24px 0}.wf-timeline-item{margin-bottom:28px;position:relative}.wf-timeline-item:before{content:"";position:absolute;left:-39px;top:6px;width:12px;height:12px;border-radius:50%;background:var(--cerulean)}.wf-timeline-item.highlight:before{background:var(--gold);width:16px;height:16px;left:-41px}.wf-timeline-item .year{font-size:11px;letter-spacing:3px;color:var(--gold);text-transform:none;margin-bottom:4px}.wf-timeline-item h4{font-size:16px;font-weight:500;color:var(--deep-navy);margin-bottom:4px}.wf-timeline-item p{font-size:13px;color:var(--muted)}.outcome-good{font-size:12px;background:#eaf5ea;border-left:3px solid #4CAF50;padding:6px 10px;margin-top:6px;color:#2e7d32}.outcome-neutral{font-size:12px;background:#fff9ed;border-left:3px solid var(--gold);padding:6px 10px;margin-top:6px;color:#7a5c00}.wf-quote{border-left:3px solid var(--gold);padding:16px 24px;background:var(--cream);margin:24px 0;font-family:Cormorant Garamond,serif;font-size:20px;font-style:italic;color:var(--deep-navy)}.wf-quote cite{display:block;font-size:12px;font-style:normal;font-family:DM Sans,sans-serif;color:var(--muted);margin-top:8px;letter-spacing:1px}.wf-ip-box{border:2px solid var(--gold);padding:28px;margin:24px 0;position:relative}.wf-ip-box .ip-label{position:absolute;top:-12px;left:20px;background:#fff;padding:0 8px;font-size:10px;letter-spacing:3px;text-transform:uppercase;color:var(--gold);font-weight:600}.wf-ip-box h4{font-family:Cormorant Garamond,serif;font-size:22px;color:var(--deep-navy);margin-bottom:8px}.wf-ip-box p{font-size:13px;color:var(--muted);font-weight:300}.wf-ip-expiry{font-size:18px;font-weight:600;color:var(--sapphire);margin-top:8px}.wf-indication-row{display:flex;flex-wrap:wrap;gap:10px;margin:20px 0}.wf-indication-pill{background:var(--cream);border:1px solid #ccc;border-radius:100px;padding:6px 16px;font-size:12px;color:var(--deep-navy);display:flex;align-items:center;gap:6px}.wf-indication-pill .dot{width:7px;height:7px;border-radius:50%;background:var(--cerulean)}.wf-indication-pill.featured-pill{background:#f8f4e8;border-color:var(--gold);font-weight:500}.wf-indication-pill.featured-pill .dot{background:var(--gold);width:9px;height:9px}.wf-cta-section{background:linear-gradient(135deg,var(--sapphire) 0%,var(--deep-navy) 100%);color:#fff;padding:60px 48px;margin:32px -40px -40px;text-align:center}.wf-cta-section h3{font-family:Cormorant Garamond,serif;font-size:40px;font-weight:300;margin-bottom:12px}.wf-cta-section p{font-size:15px;color:#fff9;margin-bottom:32px;max-width:500px;margin-left:auto;margin-right:auto}.wf-cta-section .btns{display:flex;gap:16px;justify-content:center}.wf-moa-box{background:var(--deep-navy);color:#fff;border-radius:4px;padding:28px 32px;margin:8px 0}.wf-moa-box h4{font-family:Cormorant Garamond,serif;font-size:20px;color:var(--ice);margin-bottom:12px}.wf-moa-box p{font-size:13px;color:#ffffffb3;margin-bottom:10px;font-weight:300}.wf-moa-box .scenario-label{font-size:10px;letter-spacing:3px;text-transform:uppercase;color:var(--gold);margin-bottom:6px;margin-top:16px}.wf-asset-highlight{background:linear-gradient(135deg,#0e3a1f,#0e1f38);color:#fff;border:1px solid rgba(78,160,100,.4);border-radius:4px;padding:28px 32px;margin:24px 0}.wf-asset-highlight h4{font-family:Cormorant Garamond,serif;font-size:22px;color:#8fd4a0;margin-bottom:12px}.wf-asset-highlight p{font-size:13px;color:#ffffffbf;font-weight:300;margin-bottom:8px}.wf-asset-highlight .asset-label{font-size:10px;letter-spacing:3px;text-transform:uppercase;color:#8fd4a0;margin-bottom:8px}.wf-patient-stat{background:var(--cream);border-left:3px solid var(--gold);padding:16px 20px}.wf-patient-stat .big-num{font-family:Cormorant Garamond,serif;font-size:32px;color:var(--deep-navy);font-weight:400;line-height:1;margin-bottom:4px}.wf-patient-stat .desc{font-size:12px;color:var(--muted)}.wf-patient-stat .stat-line+.stat-line{padding-top:4px;border-top:1px solid rgba(0,0,0,.04)}.wf-pipeline-row{display:grid;grid-template-columns:200px 1fr 1fr 1fr 1fr;gap:0;align-items:center;padding:16px 0;border-bottom:1px solid #e5e5e5;font-size:13px}.wf-pipeline-row.header{font-size:10px;letter-spacing:2px;text-transform:uppercase;color:var(--gold);border-bottom:2px solid var(--gold);padding-bottom:12px}.wf-pipeline-row.lead{background:#faf7ee}.wf-pipeline-indication{font-weight:500;color:var(--deep-navy);padding-left:12px}.wf-pipeline-bar{height:22px;background:var(--cream);position:relative;margin:0 4px;border-radius:2px}.wf-pipeline-bar .fill{height:100%;background:var(--cerulean);border-radius:2px}.wf-pipeline-bar .fill.gold{background:var(--gold)}.wf-pipeline-bar .fill.discovery{width:100%;background:linear-gradient(90deg,var(--ice) 0%,var(--ice) 70%,transparent 70%)}.wf-pipeline-bar .fill.preclin{width:100%;background:linear-gradient(90deg,var(--cerulean) 0%,var(--cerulean) 50%,transparent 50%)}.wf-pipeline-bar .fill.indenab{width:100%;background:linear-gradient(90deg,var(--gold) 0%,var(--gold) 80%,transparent 80%)}.page-divider{text-align:center;padding:32px;font-size:10px;letter-spacing:6px;text-transform:uppercase;color:var(--muted);background:var(--warm-white);border-top:1px solid #ddd;border-bottom:1px solid #ddd}.strategy-wrap{background:var(--deep-navy);color:#fff;padding:80px 40px}.strategy-inner{max-width:960px;margin:0 auto}.strategy-grid{display:grid;grid-template-columns:1fr 1fr;gap:32px;margin-top:40px}.strategy-card{background:#ffffff0d;border:1px solid rgba(255,255,255,.1);padding:32px;border-radius:2px}.strategy-card h4{font-family:Cormorant Garamond,serif;font-size:22px;margin-bottom:16px;color:var(--ice)}.strategy-card ul{padding-left:16px}.strategy-card li{font-size:13px;color:#fff9;margin-bottom:8px;font-weight:300}.website-content-label{background:#e8f4ea;color:#2e7d32;padding:8px 16px;font-size:10px;letter-spacing:2px;text-transform:uppercase;font-weight:600;border-left:4px solid #4caf50}.not-website-label{background:#fff3e0;color:#7a5c00;padding:8px 16px;font-size:10px;letter-spacing:2px;text-transform:uppercase;font-weight:600;border-left:4px solid var(--gold)}::-webkit-scrollbar{width:6px}::-webkit-scrollbar-track{background:var(--cream)}::-webkit-scrollbar-thumb{background:var(--muted);border-radius:3px}.v21-flag{background:#fff3e0;border-left:4px solid var(--gold);padding:20px 24px;margin:24px 0}.v21-flag h4{font-family:Cormorant Garamond,serif;font-size:20px;color:var(--deep-navy);margin-bottom:8px}.v21-flag p,.v21-flag li{font-size:13px;color:#6b5a30}.v21-flag ul{padding-left:18px;margin-top:8px}.v21-flag li{margin-bottom:6px}.new-badge{display:inline-block;background:var(--gold);color:#fff;font-size:9px;letter-spacing:2px;padding:3px 8px;margin-left:10px;vertical-align:middle;font-weight:600}.pub-controls{background:var(--deep-navy);padding:24px 28px;margin:24px -40px}.pub-controls .pub-filter-label{font-size:10px;letter-spacing:3px;text-transform:uppercase;color:var(--gold);margin-bottom:10px}.pub-filter-row{display:flex;flex-wrap:wrap;gap:8px;margin-bottom:20px}.pub-filter-btn{background:#ffffff12;border:1px solid rgba(255,255,255,.18);color:#fffc;font-family:DM Sans,sans-serif;font-size:12px;padding:7px 14px;border-radius:100px;cursor:pointer;transition:all .15s}.pub-filter-btn:hover{background:#ffffff29;color:#fff}.pub-filter-btn.active{background:var(--gold);border-color:var(--gold);color:var(--midnight);font-weight:600}.pub-filter-btn .cnt{opacity:.6;font-size:10px;margin-left:3px}.pub-count-bar{font-size:12px;color:var(--muted);padding:10px 0;border-bottom:2px solid var(--gold);margin-bottom:0}.pub-count-bar strong{color:var(--deep-navy)}table.pub-table{width:100%;border-collapse:collapse}table.pub-table thead th{font-size:10px;letter-spacing:2px;text-transform:uppercase;color:var(--gold);text-align:left;padding:12px 10px;border-bottom:2px solid var(--gold)}table.pub-table td{padding:16px 10px;border-bottom:1px solid #e8e5de;vertical-align:top}.pub-title{font-size:14px;font-weight:500;color:var(--sapphire);text-decoration:none;line-height:1.4}.pub-title:hover{color:var(--cerulean);text-decoration:underline}.pub-star{color:var(--gold);font-size:13px}.pub-meta{font-size:12px;color:var(--muted);margin-top:4px}.pub-finding{font-size:12.5px;color:var(--charcoal);margin-top:8px;line-height:1.5}.pub-quality{font-size:11.5px;color:var(--muted);margin-top:6px;font-style:italic}.pub-ind{font-size:12px;color:var(--deep-navy);font-weight:500;white-space:nowrap}.pub-studytype{font-size:11px;color:var(--muted);font-weight:400;margin-top:3px;white-space:normal}.pub-mat{white-space:nowrap}.mat-badge{display:inline-block;font-size:10px;letter-spacing:1px;padding:5px 10px;border-radius:2px;font-weight:600;text-transform:uppercase}.mat-vepo{background:var(--gold);color:#fff}.mat-both{background:#2e7d32;color:#fff}.mat-commercial{background:var(--cerulean);color:#fff}.mat-unpurified{background:#b5651d;color:#fff}.mat-unspec,.mat-other{background:#ddd9d0;color:#5a5a5a}.mat-na{background:#f0ede6;color:#9a9a9a}.pub-legend{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));row-gap:14px;column-gap:20px;margin:20px 0;padding:18px 20px;background:var(--cream);border-radius:2px}.pub-legend-item{font-size:12px;color:var(--muted);display:flex;align-items:center;gap:8px}.team-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:20px;margin:24px 0}.team-grid-2{display:grid;grid-template-columns:repeat(2,1fr);gap:20px;margin:24px 0}.person-card{background:var(--warm-white);border:1px solid #e0ddd6;padding:24px;border-radius:2px}.person-card.chair{background:linear-gradient(135deg,#f8f4e8,#faf7ee);border:1px solid var(--gold)}.person-avatar{width:52px;height:52px;border-radius:50%;background:var(--deep-navy);color:var(--ice);display:flex;align-items:center;justify-content:center;font-family:Cormorant Garamond,serif;font-size:20px;margin-bottom:14px}.person-card.chair .person-avatar{background:var(--gold);color:#fff}.person-name{font-family:Cormorant Garamond,serif;font-size:21px;color:var(--deep-navy);font-weight:600;margin-bottom:2px}.person-role{font-size:10px;letter-spacing:2px;text-transform:uppercase;color:var(--gold);margin-bottom:10px;font-weight:600}.person-affil{font-size:12px;color:var(--sapphire);font-weight:500;margin-bottom:8px}.person-bio{font-size:12.5px;color:var(--muted);font-weight:300;line-height:1.55}.person-tags{display:flex;flex-wrap:wrap;gap:6px;margin-top:12px}.person-tag{font-size:9px;letter-spacing:1px;text-transform:uppercase;background:var(--cream);border:1px solid #ddd;color:var(--muted);padding:3px 8px}.person-link{display:inline-block;font-size:11px;color:var(--cerulean);margin-top:10px;text-decoration:none;border-bottom:1px dotted var(--cerulean)}.doc-list{padding-left:18px;margin-top:10px}.doc-list li{font-size:14px;color:var(--muted);font-weight:300;margin-bottom:10px;line-height:1.6}html{scroll-behavior:smooth}body{margin:0}a{text-decoration:none}.page-shell{min-height:100vh}.container{max-width:1100px;margin:0 auto;width:min(calc(100% - 2rem),1100px)}.page-content-wrap{background:var(--cream);padding:48px 40px 0}.page-content-wrap .wireframe{margin-bottom:0;max-width:1200px}.page-header{background:#fff;border-bottom:1px solid #e6e0d6;position:sticky;top:0;z-index:50;padding:1.35rem 0 1.1rem}.header-top{display:flex;align-items:center;justify-content:space-between;gap:1rem}.logo-link{display:inline-flex;align-items:center}.site-logo{display:block;width:auto;max-width:200px;height:auto}.header-cta{white-space:nowrap}.header-nav{display:flex;align-items:center;justify-content:center;gap:2.5rem;margin-top:1.5rem;flex-wrap:wrap}.header-nav a{color:var(--gold);font-size:1rem;font-weight:600;letter-spacing:.08em;text-transform:uppercase}.header-nav a:hover{color:var(--deep-navy)}.button{display:inline-flex;align-items:center;justify-content:center;min-height:2.75rem;padding:.75rem 1.25rem;letter-spacing:.06rem;text-transform:uppercase;font-size:.82rem;border:1px solid transparent;cursor:pointer}.button.primary{background:var(--gold);color:#fff}.button.dark-outline{border-color:#0e1f3840;color:var(--deep-navy)}.nav-toggle{display:none;flex-direction:column;justify-content:center;align-items:center;gap:4px;width:44px;height:44px;background:transparent;border:1px solid rgba(14,31,56,.18);border-radius:4px;cursor:pointer}.nav-toggle-line{display:block;width:18px;height:2px;background:var(--deep-navy)}.page-intro{margin-bottom:28px}.page-intro .wf-hero-kicker{color:var(--gold);font-size:11px;letter-spacing:4px;text-transform:uppercase;margin-bottom:14px}.page-intro h1{font-family:Cormorant Garamond,serif;font-size:clamp(40px,5vw,58px);line-height:1.02;font-weight:600;color:var(--deep-navy);max-width:1000px;margin-bottom:24px}.page-intro>p{font-size:16px!important;line-height:1.7;max-width:1050px}.page-jump-nav{display:flex;flex-wrap:wrap;align-items:center;justify-content:center;gap:0;margin:0 0 36px;padding:14px 0;border-top:1px solid #ddd7cd;border-bottom:1px solid #ddd7cd}.page-jump-nav a{color:var(--deep-navy);font-size:12px;font-weight:600;letter-spacing:.08em;text-transform:uppercase;padding:4px 16px;border-right:1px solid #d9d2c7}.page-jump-nav a:first-child{padding-left:16px}.page-jump-nav a:last-child{border-right:0}.page-jump-nav a:hover{color:var(--cerulean)}#mechanisms,#clinical-windows,#why-lead-program,#what-som-does,#why-vepoloxamer-fits,#phase-3-trials,#path-to-liferaft,#commercial-exclusivity,#scientific-advisory-board,#board-of-directors{scroll-margin-top:190px}.card-heading{display:flex;align-items:flex-start;gap:12px;margin-bottom:10px}.wf-card .card-heading .card-icon{flex:0 0 auto;margin:0;line-height:1}.wf-card .card-heading h4{margin:0;line-height:1.15}.wf-hero{background:linear-gradient(135deg,var(--midnight) 0%,var(--deep-navy) 60%,var(--sapphire) 100%);color:#fff;padding:60px 48px;margin:-40px -40px 32px;position:relative;overflow:hidden}.wf-hero:has(.wf-hero-art){display:grid;grid-template-columns:minmax(0,1fr) 420px;grid-template-areas:"kicker image" "title image" "body image" "buttons image" "stats stats";column-gap:3rem;row-gap:0;align-items:start}.wf-hero:has(.wf-hero-art)>.wf-hero-kicker{grid-area:kicker}.wf-hero:has(.wf-hero-art)>h2{grid-area:title;max-width:620px}.wf-hero:has(.wf-hero-art)>p{grid-area:body;max-width:560px}.wf-hero:has(.wf-hero-art)>.wf-hero-btns{grid-area:buttons}.wf-hero:has(.wf-hero-art)>.wf-hero-stats{grid-area:stats;width:100%}.wf-hero-art{grid-area:image;align-self:start;justify-self:end;width:100%;max-width:420px;height:450px;background-image:url(/images/liferaft-home-page-image-patient.jpg);background-size:cover;background-position:center;background-repeat:no-repeat;-webkit-mask-image:linear-gradient(to left,black 75%,transparent 100%),linear-gradient(to right,black 75%,transparent 100%),linear-gradient(to top,black 80%,transparent 100%),linear-gradient(to bottom,black 80%,transparent 100%);-webkit-mask-composite:destination-in;mask-image:linear-gradient(to left,black 75%,transparent 100%),linear-gradient(to right,black 75%,transparent 100%),linear-gradient(to top,black 80%,transparent 100%),linear-gradient(to bottom,black 80%,transparent 100%);mask-composite:intersect}.wf-hero-stats .wf-stat{flex:1 1 0;min-width:140px}.wf-hero--centered{display:block!important;text-align:center;padding:80px 48px}.wf-hero--centered h2{max-width:680px;margin:0 auto 20px}.wf-hero--centered>p{max-width:650px;margin:0 auto 10px}.wf-hero--centered .wf-hero-art{display:none!important}.pub-table-scroll{width:100%;overflow-x:auto;-webkit-overflow-scrolling:touch}.pub-table-scroll table.pub-table{min-width:780px}.pub-filter-btn{appearance:none}.wf-form{margin-top:24px}.wf-form-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px}.wf-field{display:flex;flex-direction:column}.wf-field--full{grid-column:1 / -1}.wf-field label{font-size:11px;letter-spacing:2px;text-transform:uppercase;color:var(--gold);margin-bottom:8px;font-weight:600}.wf-field input,.wf-field select,.wf-field textarea{width:100%;padding:14px 16px;border:1px solid #d0ccc4;background:#fff;color:var(--deep-navy);font-family:DM Sans,sans-serif;font-size:14px}.wf-field textarea{resize:vertical;min-height:160px}.wf-form-actions{margin-top:20px}.wf-form-actions .wf-btn-primary{border:0}.footer-main{background:var(--warm-white);padding:2.4rem 0 2rem;border-top:1px solid #ddd7cd}.footer-main-inner{display:grid;grid-template-columns:1.2fr 2fr 1fr;gap:2rem;align-items:start}.footer-brand{font-family:Cormorant Garamond,serif;font-size:2rem;color:var(--deep-navy);line-height:1}.footer-tagline{margin-top:7px;font-size:12px;line-height:1.45;color:var(--muted);font-family:DM Sans,sans-serif}.footer-col-title{font-size:.7rem;letter-spacing:.18rem;text-transform:uppercase;color:var(--gold);font-weight:700;margin-bottom:.9rem}.footer-links{display:grid;gap:.7rem}.footer-links.two-col{grid-template-columns:repeat(2,minmax(0,1fr));gap:.7rem 2rem}.footer-links a{color:var(--deep-navy);font-size:.95rem}.footer-actions{display:flex;flex-direction:column}.footer-legal{margin-top:1.2rem;padding-top:1rem;border-top:1px solid #ddd7cd;color:var(--muted);font-size:.8rem;line-height:1.6}.footer-legal a{color:var(--deep-navy);text-decoration:underline}@media(max-width:1050px){.wf-pipeline-row{grid-template-columns:180px 1fr 1fr 1fr 1fr}.team-grid{grid-template-columns:repeat(2,1fr)}}@media(max-width:960px){.header-cta{display:none}.nav-toggle{display:flex;margin-left:auto}.header-nav{display:none;flex-direction:column;align-items:flex-start;gap:0;width:100%;margin-top:1rem}.header-nav.is-open{display:flex}.header-nav a{width:100%;padding:.85rem 0;border-top:1px solid #e6e0d6}.site-logo{max-width:220px}.page-content-wrap{padding:24px 12px 0}.wireframe{padding:24px}.wf-grid-4{grid-template-columns:repeat(2,1fr)}.wf-grid-3,.wf-grid-2,.team-grid,.team-grid-2{grid-template-columns:1fr}.wf-hero:has(.wf-hero-art){display:block}.wf-hero-art{display:none}.wf-hero{padding:40px 24px}.wf-hero h2,.wf-hero>p{max-width:none}.wf-hero-btns{flex-wrap:wrap}.wf-hero-stats{display:grid;grid-template-columns:repeat(2,1fr);gap:24px 16px}.wf-pipeline-row{min-width:760px}.wireframe>div:has(>.wf-pipeline-row){overflow-x:auto;-webkit-overflow-scrolling:touch}.footer-main-inner,.footer-links.two-col{grid-template-columns:1fr}}@media(max-width:640px){.page-header{padding:1rem 0}.site-logo{max-width:185px}.page-intro h1{font-size:38px}.page-jump-nav{display:block}.page-jump-nav a{display:block;padding:8px 0;border-right:0;border-bottom:1px solid #e5dfd5}.page-jump-nav a:last-child{border-bottom:0}.wf-hero{padding:32px 20px;margin-left:-24px;margin-right:-24px}.wf-hero h2{font-size:34px}.wf-hero-btns .wf-btn-primary,.wf-hero-btns .wf-btn-secondary{width:100%;text-align:center;justify-content:center}.wf-hero-stats,.wf-grid-4,.wf-form-grid{grid-template-columns:1fr}.wf-field--full{grid-column:auto}.pub-controls{margin-left:-24px;margin-right:-24px;padding:20px 24px}}.footer-logo-wrap{display:flex;align-items:flex-start}.footer-logo{display:block;width:auto;max-width:220px;height:auto}.science-flowchart{display:flex;justify-content:center;margin:32px auto 48px}.science-flowchart img{display:block;width:100%;height:auto}.tissue-cascade-note{margin-top:-8px;margin-bottom:40px}.tissue-cascade-note p{font-size:14px;max-width:1100px}.lead-program-image-wrap{flex:0 0 280px;order:2;margin-left:auto}.lead-program-image{display:block;width:280px;height:240px;object-fit:cover;object-position:center;border-radius:4px}@media(max-width:960px){.footer-logo{max-width:200px}.lead-program-image-wrap{flex:1 1 100%;margin-left:0}.lead-program-image{width:100%;max-width:420px;height:auto;margin:0 auto}}@media(max-width:640px){.page-jump-nav,.page-jump-nav a{text-align:center}}.header-nav a.is-active,.header-nav a[aria-current=page]{color:var(--deep-navy)}.person-photo{display:block;width:100%;aspect-ratio:3 / 4;object-fit:cover;object-position:center 18%;margin-bottom:20px;border-radius:2px}.home-hero h2{font-size:clamp(58px,5.5vw,78px);max-width:880px;line-height:1.02}@media(max-width:960px){.home-hero h2{font-size:clamp(48px,8vw,62px)}}@media(max-width:640px){.home-hero h2{font-size:42px}}@media(max-width:960px){.wf-hero:has(.wf-hero-art){display:block}.wf-hero-art{display:none}.wf-hero:has(.wf-hero-art)>h2,.wf-hero:has(.wf-hero-art)>p,.wf-hero:has(.wf-hero-art)>.wf-hero-btns,.wf-hero:has(.wf-hero-art)>.wf-hero-stats{width:100%;max-width:none}.wf-hero:has(.wf-hero-art)>.wf-hero-btns{display:flex;flex-wrap:wrap;gap:12px}.wf-hero:has(.wf-hero-art)>.wf-hero-stats{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:24px 16px;margin-top:36px}}@media(max-width:560px){.wf-hero:has(.wf-hero-art){padding:36px 20px}.wf-hero:has(.wf-hero-art)>.wf-hero-btns{flex-direction:column}.wf-hero:has(.wf-hero-art)>.wf-hero-btns .wf-btn-primary,.wf-hero:has(.wf-hero-art)>.wf-hero-btns .wf-btn-secondary{width:100%;text-align:center;justify-content:center}.wf-hero:has(.wf-hero-art)>.wf-hero-stats{grid-template-columns:1fr;gap:20px}}@media(min-width:961px){.page-header{padding:1.15rem 0}.header-top{justify-content:flex-start}.header-nav{margin:0 0 0 3rem;gap:2rem;flex:1;justify-content:flex-start}}.opportunity-lines{margin:22px 0 4px;text-align:center;color:var(--deep-navy)}.opportunity-line{padding:9px 0;font-size:13px;border-top:1px solid #ddd7cd}.opportunity-line:last-child{border-bottom:1px solid #ddd7cd}.opportunity-line span{color:var(--gold);padding:0 10px}.opportunity-line--primary{font-weight:600}.clinical-window-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:20px;margin-top:24px}.clinical-window-card{background:var(--warm-white);border:1px solid #e0ddd6;padding:24px}.clinical-window-card h4{font-family:Cormorant Garamond,serif;font-size:22px;color:var(--deep-navy);margin-bottom:10px}.patient-voice{margin:28px 0 8px;padding:26px 30px;background:var(--cream);border-left:3px solid var(--gold)}.patient-voice blockquote{font-family:Cormorant Garamond,serif;font-size:24px;line-height:1.35;font-style:italic;color:var(--deep-navy);margin:0 0 10px}.patient-voice p{font-size:12px;color:var(--muted);margin:0}@media(max-width:960px){.clinical-window-grid{grid-template-columns:1fr}}.page-header{padding:.75rem 0}.site-logo{max-width:170px}@media(min-width:961px){.page-header{padding:.75rem 0}.header-nav{margin:0 0 0 2rem;gap:1.35rem}.header-nav a{font-size:.86rem}}.card-icon{width:22px;height:22px;flex:0 0 22px;display:flex;align-items:center;justify-content:center}.card-icon img{display:block;width:20px;height:20px;object-fit:contain}.home-hero .wf-hero-art{background-position:center}.tissue-cascade-intro{margin-top:30px;margin-bottom:12px}.tissue-cascade-intro h3{margin-bottom:8px}.tissue-cascade-intro p{font-size:16px;color:var(--charcoal);max-width:none}.tissue-cascade-flow{width:100%;max-width:none;margin-top:12px}.clinical-window-label{margin-top:22px;font-size:10px;letter-spacing:2px;text-transform:uppercase;color:var(--gold);font-weight:700}.pipeline-table-wrap{overflow-x:auto;-webkit-overflow-scrolling:touch}.investor-sections .wf-block{border-top:1px solid #ddd7cd;padding-top:28px}.legal-page{padding:3rem 0 5rem}.legal-page .copy{max-width:900px}.legal-page h1{font-family:Cormorant Garamond,serif;font-size:clamp(42px,5vw,58px);color:var(--deep-navy);margin-bottom:18px}.legal-page h2{font-family:Cormorant Garamond,serif;font-size:28px;color:var(--deep-navy);margin:32px 0 10px}.legal-page h3{font-size:16px;color:var(--deep-navy);margin:20px 0 8px}.legal-page p,.legal-page li{color:var(--muted)}.legal-page ul{padding-left:22px;margin:10px 0 18px}@media(max-width:960px){.site-logo{max-width:190px}}.investor-presentation-button{margin-top:18px}.pipeline-market-note{margin-top:16px;font-size:12px;font-style:italic;color:#ffffffb8}.person-linkedin{margin-top:10px;margin-bottom:10px}.person-linkedin a{font-size:12px;font-weight:600}.home-feature-cards .wf-card{background:linear-gradient(135deg,#f8f4e8,#faf7ee);border-color:var(--gold);text-align:center}.home-feature-cards .wf-card.featured{background:linear-gradient(135deg,#f8f4e8,#faf7ee);border-color:var(--gold)}.home-feature-cards .wf-card .card-heading{justify-content:center}.home-feature-cards .wf-card p,.home-feature-cards .wf-card a.pub-link{font-size:14px}.home-publications{display:grid;grid-template-columns:minmax(0,2fr) minmax(220px,1fr);gap:32px;align-items:start}.home-publications-copy{grid-column:1}.home-publication-stat-block{grid-column:2;grid-row:1 / span 2;display:flex;flex-direction:column;gap:14px;margin:0!important}.home-publication-stat-block .stat-line{display:flex;align-items:baseline;gap:14px}.home-publication-stat-block .desc{font-size:14px}.home-publications-link{grid-column:1;font-size:14px!important;align-self:start}.science-mechanism-grid .wf-card p{font-size:14px}.science-mechanism-grid .mechanism-subhead{font-size:13px;line-height:1.4;color:var(--deep-navy);font-weight:600;margin:2px 0 10px}.tissue-cascade-intro p{font-size:14px}.pipeline-som-band{text-align:center}.pipeline-som-band>div{justify-content:center!important}.pipeline-som-band>div>div{max-width:720px}.pipeline-som-band p{margin-left:auto;margin-right:auto}.som-effects-layout{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:32px;align-items:start}.som-effects-copy{grid-column:1}.som-effects-stat-block{grid-column:2;grid-row:1;display:flex;flex-direction:column;gap:14px;margin:0}.som-effects-stat-block .stat-line{display:flex;align-items:center;gap:14px;flex-wrap:wrap}.som-effects-stat-block .desc{font-size:14px}.som-effects-stat-block .big-num{font-family:Georgia,Times New Roman,serif;font-variant-numeric:lining-nums tabular-nums}.patient-perspectives-band{background:var(--deep-navy);color:#fff;padding:36px 40px;margin:28px -40px;text-align:center}.patient-perspectives-band .patient-perspectives-intro{font-size:14px;color:#ffffffc7;margin:0 auto 20px;max-width:820px}.patient-perspectives-band blockquote{font-family:Cormorant Garamond,serif;font-size:26px;line-height:1.35;font-style:normal;margin:0 0 12px;color:#fff}.patient-perspectives-band .patient-perspectives-source{font-size:13px;color:#ffffffb8}.patient-perspectives-band a,.patient-perspectives-band a:visited{color:#fff;border-bottom:1px dotted rgba(255,255,255,.7);text-decoration:none}.som-impact-grid .wf-card{background:linear-gradient(135deg,#f8f4e8,#faf7ee);border-color:var(--gold)}.som-impact-grid .wf-card p,#why-vepoloxamer-fits+.wf-grid-3 .wf-card p,#why-vepoloxamer-fits~.wf-grid-3 .wf-card p{font-size:14px}.burn-injury-layout{display:grid;grid-template-columns:minmax(0,2fr) minmax(220px,1fr);gap:32px;align-items:start}.burn-injury-copy{grid-column:1}.burn-injury-image{grid-column:2}.burn-injury-image img{display:block;width:100%;aspect-ratio:4/3;object-fit:cover;border-radius:2px}.story-summary-grid .wf-card p{font-size:14px}.story-dark-band{display:grid;grid-template-columns:minmax(0,2fr) minmax(220px,1fr);gap:32px;align-items:center}.story-dark-copy{min-width:0}.story-dark-image img{display:block;width:100%;aspect-ratio:4/3;object-fit:cover;border-radius:2px}.story-dark-image{position:relative;overflow:hidden}.story-dark-image img{display:block;width:100%;height:auto}.story-dark-image:after{content:"";position:absolute;top:0;right:0;bottom:0;width:35%;pointer-events:none;background:linear-gradient(to right,#0e1f3800,#0e1f38)}.story-dark-band .story-citations a,.story-dark-band .story-citations a:visited{color:#fff}.story-timeline{margin-left:50px;margin-right:50px}.ip-protection-grid .wf-ip-box p{font-size:14px}.contact-gold-card{background:linear-gradient(135deg,#f8f4e8,#faf7ee);border-color:var(--gold)}.contact-channel-grid .wf-card p,.contact-channel-grid .wf-card a.pub-link{font-size:14px}@media(max-width:960px){.home-publications,.som-effects-layout,.burn-injury-layout,.story-dark-band{grid-template-columns:1fr}.home-publications-copy,.home-publication-stat-block,.home-publications-link,.som-effects-copy,.som-effects-stat-block,.burn-injury-copy,.burn-injury-image{grid-column:1;grid-row:auto}.story-timeline{margin-left:18px;margin-right:18px}}@media(min-width:961px){.page-header{padding:.35rem 0}.site-logo{max-width:145px}.header-nav{margin-left:1.75rem}}.page-disclaimers{margin-top:42px;padding-top:18px;border-top:1px solid #ddd7cd;color:var(--muted);font-size:.8rem;line-height:1.6}.page-disclaimers p{margin:0 0 10px;font-size:inherit;color:inherit}.page-disclaimers p:last-child{margin-bottom:0}